5. PRINCIPLES OF INHERITANCE AND VARIATION
INHERITANCE OF ONE GENE
3 Tall: 1 Dwarf = 3:1
Monohybrid genotypic ratio:
Monohybrid genotypic ratio:
1 Homozygous tall (TT)
2 Heterozygous tall (Tt)
1 Homozygous dwarf (tt)
2 Heterozygous tall (Tt)
1 Homozygous dwarf (tt)
= 1:2:1
Mendel made similar observations for other pairs of traits. He proposed that some factors were inherited from parent to offspring. Now it is called as genes.
Mendel made similar observations for other pairs of traits. He proposed that some factors were inherited from parent to offspring. Now it is called as genes.
Do not use T for tall and d for dwarf because it is difficult to remember whether T & d are alleles of same gene or not.The F1 (Tt) when self-pollinated, produces gametes T and t in equal proportion. During fertilization, pollen grains of T have 50% chance to pollinate eggs of T & t. Also, pollen grains of t have 50% chance to pollinate eggs of T and t.
1/4th of the random fertilization leads to TT (¼ TT).
1/2 (2/4) of the random fertilization leads to Tt (½ Tt).
1/4th of the random fertilization leads to tt (¼ tt).
Tt x Tt
Binomial expression = (ax + by) 2Hence (½ T + ½ t) 2= (½ T + ½ t) (½ T + ½ t)= ¼ TT + ¼ Tt + ¼ Tt + ¼ tt= ¼ TT + ½ Tt + ¼ tt
Mendel self-pollinated the F2 plants.
He found that dwarf F2 plants continued to generate dwarf plants in F3 & F4.
He concluded that genotype of the dwarfs was homozygous- tt.
Back cross and Test cross
Testcross: Crossing of an organism with dominant phenotype to a recessive individual. E.g.
Hence monohybrid test cross ratio= 1:1
Test cross is used to find out the unknown genotype of a character. E.g.Hence monohybrid test cross ratio= 1:1
Mendel conducted test cross to determine the F2 genotype.
Mendel’s Principles or Laws of Inheritance
1. First Law (Law of Dominance)
- Characters are controlled by discrete units called factors.
- Factors occur in pairs.
- In a dissimilar pair of factors, one member of the pair dominates (dominant) the other (recessive).
“During gamete formation, the factors (alleles) of a character pair present in parents segregate from each other such that a gamete receives only one of the 2 factors”.
Homozygous parent produces similar gametes.
Heterozygous parent produces two kinds of gametes.
Heterozygous parent produces two kinds of gametes.
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