10. MICROBES IN HUMAN
WELFARE
1. MICROBES IN HOUSEHOLD PRODUCTS
· Lactobacillus or Lactic
acid bacteria (LAB):
-
It converts milk to curd
by producing acids that coagulate and partially digest the milk proteins.
-
Fresh milk can be
converted to curd by adding some curd containing LAB. It also increases vitamin
B12 in curd.
-
In stomach, LAB helps to
check pathogens.
· Bacterial fermentation (anaerobic
respiration) in dough is used to make foods such
as dosa, idli etc. The puffed-up
appearance of dough is due to the production of CO2.
· Baker’s Yeast (Saccharomyces cerevisiae):
It is used to make bread by fermenting dough.
· Toddy is
made by fermenting sap from palms.
· Microbes
are used to ferment fish, soya bean & bamboo-shoots and to produce cheeses.
· Swiss cheese
has large holes due to production of CO2 by Propionibacterium sharmanii (a
bacterium).
Roquefort cheese
is ripened by growing a fungus (Penicillium
roqueforti) on them.
2. MICROBES IN INDUSTRIAL PRODUCTS
Production of beverages, antibiotics etc. on an
industrial scale, requires growing microbes in very large vessels (fermentors).
Fermented beverages
-
Saccharomyces cerevisiae
(Brewer’s yeast) is used in the
production of beverages by fermenting malted cereals and fruit juices to
produce ethanol.
-
Wine & Beer are
produced without distillation.
-
Whisky, Brandy, Rum, Gin,
Arrack etc. are produced by distillation of fermented broth.
Antibiotics
-
Chemical substances
produced by some microbes and can kill or retard the growth of pathogens.
-
They are used to treat
plague, whooping cough, diphtheria, leprosy etc.
-
Penicillin:
First antibiotic discovered by Alexander
Fleming. He observed that Staphylococci
could not grow around a mould (Penicillium
notatum) growing in unwashed culture plates. He extracted penicillin from
it.
-
Earnest
Chain and Howard
Florey established its full potential as an effective antibiotic.
-
Fleming,
Chain & Florey were awarded Nobel Prize (1945).
Chemicals, enzymes & other bioactive
molecules
1.
Organic
acids: Acid producer
microbes include
Aspergillus niger
(a fungus) : Citric acid
Acetobacter aceti
(a bacterium) : Acetic acid
Clostridium butylicum
(a bacterium) : Butyric acid
Lactobacillus (a
bacterium) : Lactic acid
2. Alcohol: Yeast (S.
cerevisiae) is used to produce ethanol.
3.
Enzymes:
·
Lipases:
Used in detergent formulations. Help to remove oily stains from the laundry.
·
Pectinases
& Proteases: To clarify bottled juices.
·
Streptokinase:
Produced by Streptococcus. Used as a ‘clot
buster’ to remove clots from the blood vessels of patients who have myocardial infarction.
4.
Cyclosporine
A: Produced by Trichoderma polysporum
(fungus). Used as an immunosuppressive
agent in organ transplant patients.
5. Statins: Produced by Monascus purpureus (a yeast). Used as blood-cholesterol lowering agents. It inhibits the enzymes responsible for synthesis of cholesterol.
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