NEET Topic-wise & A
Topic 1: HUMAN MUSCULAR SYSTEM
NEET: Previous Years Questions
01. Three types of muscles are given as a, b and c. Identify the correct matching pair along with their location in human body:
Name of muscle/location.
(1) (a) Smooth - Toes
(b) Skeletal - Legs
(c) Cardiac - Heart
(2) (a) Skeletal - Triceps
(b) Smooth - Stomach
(c) Cardiac - Heart
(3) (a) Skeletal - Biceps
(b) Involuntary - Intestine
(c) Smooth - Heart
(4) (a) Involuntary - Nose tip
(b) Skeletal - Bone
(c) Cardiac - Heart (NEET 2024)
✅ (2) (a) Skeletal - Triceps (b) Smooth - Stomach (c) Cardiac - Heart
02. Which of the following statements are correct regarding skeletal muscle? (NEET 2023)
A. Muscle bundles are held together by collagenous connective tissue layer called fascicle.
B. Sarcoplasmic reticulum of muscle fibre is a store house of calcium ions.
C. Striated appearance of skeletal muscle fibre is due to distribution pattern of actin and myosin proteins.
D. M line is considered as functional unit of contraction called sarcomere.
Choose the most appropriate answer from the options given below:
(1) B and C only
(2) A, C and D only
(3) C and D only
(4) A, B and C only
✅ (1) B and C only
03. Which of the following statements wrongly represents the nature of smooth muscle?
(1) These muscles have no striations
(2) They are involuntary muscles
(3) Communication among the cells is performed by intercalated discs
(4) These muscles are present in the wall of blood vessels (NEET 2021)
✅ (3) Communication among the cells is performed by intercalated discs
04. During muscular contraction which of the following events occur? (NEET 2021)
(a) 'H' zone disappears
(b) 'A' band widens
(c) 'I' band reduces in width
(d) Myosin hydrolyzes ATP, releasing the ADP and Pi
(e) Z-lines attached to actins are pulled inwards
Choose the correct answer from the options given below.
(1) (a), (c), (d), (e) only
(2) (a), (b), (c), (d) only
(3) (b), (c), (d), (e) only
(4) (b), (d), (e), (a) only
✅ (1) (a), (c), (d), (e) only
05. The ciliated epithelial cells are required to move particles or mucus in a specific direction. In humans, these cells are mainly present in:
(1) Bile duct and Bronchioles
(2) Fallopian tubes and Pancreatic duct
(3) Eustachian tube and Salivary duct
(4) Bronchioles and Fallopian tubes (NEET 2019)
✅ (4) Bronchioles and Fallopian tubes
06. Calcium is important in skeletal muscle contraction because it
(1) binds to troponin to remove the masking of active sites on actin for myosin.
(2) activates the myosin ATPase by binding to it.
(3) detaches the myosin head from the actin filament.
(4) prevents the formation of bonds between the myosin cross bridges and the actin filament. (NEET 2018)
✅ (1) binds to troponin to remove the masking of active sites on actin for myosin
07. Name the ion responsible for unmasking of active sites for myosin for cross-bridge activity during muscle contraction.
(1) Calcium
(2) Magnesium
(3) Sodium
(4) Potassium (NEET-II 2016)
✅ (1) Calcium
08. Lack of relaxation between successive stimuli in sustained muscle contraction is known as
(1) tetanus
(2) tonus
(3) spasm
(4) fatigue (NEET-I 2016)
✅ (1) tetanus
Model Questions
09. Which of the following does not show amoeboid movement in human?
(1) Macrophages
(2) Neutrophils
(3) Monocytes
(4) Spermatozoa
✅ (4) Spermatozoa
10. Muscles constitute ………………. % of the body weight
(1) 40-50
(2) 60-70
(3) 65-75
(4) 25
✅ (1) 40-50
11. Which of the following statement is wrong?
(1) Visceral muscles and cardiac muscles are involuntary and non-fatigue
(2) Skeletal muscles and cardiac muscles are striated and have more mitochondria
(3) Skeletal muscles and smooth muscles are multinucleate and have rich blood supply
(4) Cardiac muscles and visceral muscles are non-fatigue and uninucleate
✅ (3) Skeletal muscles and smooth muscles are multinucleate and have rich blood supply
12. In a smooth muscle, striations are not seen because
(1) It is not attached with skeleton
(2) It has no actin & myosin
(3) Actin & myosin are not aggregated into filaments
(4) Actin & myosin form invisible filaments
✅ (3) Actin & myosin are not aggregated into filaments
13. Anisotropic band proteins are
(1) Actin and myosin only
(2) Actin and tropomyosin only
(3) Actin, myosin and tropomyosin
(4) Actin, myosin, troponin and tropomyosin
✅ (4) Actin, myosin, troponin and tropomyosin
14. Identify A, B & C in the given diagram.
(1) A –Tropomyosin, B – F actin, C – Troponin
(2) A – Myosin, B – F actin, C –Troponin
(3) A – Troponin, B – Myosin, C – F actin
(4) A – Troponin, B – Tropomyosin, C – F actin
✅ (4) A – Troponin, B – Tropomyosin, C – F actin
15. The calcium receptive protein of the muscle is
(1) Myosin
(2) Actin
(3) Tropomyosin
(4) Troponin
✅ (4) Troponin
16. Analyze the statements given below:
i. A-bands of the muscle is dark and contain myosin
ii. I-bands are the light bands and contain actin
iii. During muscle contraction, the A-band contracts
iv. The part b/w the two Z-lines is called sarcomere
v. The central part of thin filament, not overlapped by thick filament is called H-zone
Of the above statements,
(1) 1 & 2 are correct
(2) 1,3 & 5 are correct
(3) 1,2 & 3 are correct
(4) 1,2 & 4 are correct
✅ (4) 1,2 & 4 are correct
17. Select the wrong statement.
(1) Sarcomeres are the structural and functional unit of a muscle
(2) Striated and cardiac muscles are highly vascular
(3) In smooth muscles, mitochondria and glycogen granules are high
(4) Depressors are the muscles that lower a body part
✅ (3) In smooth muscles, mitochondria and glycogen granules are high
18. HMM contains
(1) Globular head + short arm
(2) Globular head + troponin
(3) Globular actin + troponin
(4) Globular actin + short arm
✅ (1) Globular head + short arm
19. Diagrammatic representation of Meromyosin is given. Label A, B, C, D and E.
(1) A=HMM, B= ATP binding sites, C= Actin binding sites, D= Head, E= LMM
(2) A=HMM, B= Actin binding sites, C= ATP binding sites, D= Head, E= LMM
(3) A=LMM, B= ATP binding sites, C=Head, D= Actin binding sites, E= HMM
(4) A=LMM, B= ATP binding sites, C= Actin binding sites, D= Head, E= HMM
✅ (4) A=LMM, B= ATP binding sites, C= Actin binding sites, D= Head, E= HMM
20. During muscle contraction
(1) Chemical energy is changed to electrical energy
(2) Chemical energy is changed to mechanical energy
(3) Chemical energy is changed to physical energy
(4) Mechanical energy is changed to chemical energy
✅ (2) Chemical energy is changed to mechanical energy
21. If sliding filament theory is true, choose the correct statement.
(1) The sarcomere length remains unchanged
(2) The distance between two adjacent Z lines remains unchanged
(3) The A-band length remains unchanged
(4) During fibre contraction both A band and I band shortens
✅ (3) The A-band length remains unchanged
22. Arrange the following steps of muscle contraction in the sequence of events occurring first.
I. Receptor sites on sarcolemma
II. Nerve impulse
III. Release of Ca2+
IV. Acetyl choline release
V. Shortening of sarcomere
VI. Synaptic cleft
VII. Spread of impulse over sarcolemma on T-tubule
The correct option is
(1) II → IV → VI → I → VII → III → V
(2) VI → II → IV → I → III → VII → V
(3) II → I → IV → VI → VII → V → III
(4) IV → II → I → VI → VII → V → III
✅ (1) II → IV → VI → I → VII → III → V
23. Regarding the figure given, choose the true statement.
(1) It represents relaxed sarcomeres and H-zone is disappeared.
(2) It represents contracted sarcomeres and H-zone is disappeared.
(3) It represents contracted sarcomeres and H-zone is clearly seen.
(4) It represents relaxed sarcomeres and H-zone is clearly seen.
✅ (2) It represents contracted sarcomeres and H-zone is disappeared.
24. Pick out the wrong statement about white muscles
(1) They contain high amount of myoglobin
(2) They undergo anaerobic metabolism
(3) Fast contraction for short period
(4) They contain lesser amount of mitochondria
✅ (1) They contain high amount of myoglobin
25. The breakdown of glycogen to pyruvic acid is called
(1) Glycogenesis
(2) Glyconeogenesis
(3) Glycogenolysis
(4) Glycolysis
✅ (3) Glycogenolysis
26. Substance that accumulates in a fatigued muscle is
(1) Pyruvic acid
(2) Lactic acid
(3) ADP
(4) CO2
✅ (2) Lactic acid
Topic 2: HUMAN SKELETAL SYSTEM
NEET: Previous Years Questions
27. Match List I with List II: (NEET 2024)
Choose the correct answer from the options given below:
(1) A-IV, B-II, C-III, D-I
(2) A-I, B-III, C-II, D-IV
(3) A-II, B-III, C-I, D-IV
(4) A-III, B-I, C-IV, D-II
✅ (4) A-III, B-I, C-IV, D-II
28. Match List I with List II. (NEET 2023)
Choose the correct answer from the options given below:
(1) A-II, B-IV, C-I, D-III
(2) A-I, B-IV, C-III, D-II
(3) A-II, B-IV, C-III, D-I
(4) A-III, B-I, C-II, D-IV
✅ (1) A-II, B-IV, C-I, D-III
29. Match the following columns and select the correct option.
✅ (2) (iv) (iii) (i) (ii)
30. Match List - I with List - II. (NEET 2021)
Choose the correct answer from the options given below.
✅ (4) (iv) (iii) (ii) (i)
31. Select the correct option. (NEET 2019)
(1) 8th, 9th and 10th pairs of ribs articulate directly with the sternum.
(2) 11th and 12th pairs of ribs are connected to the sternum with the help of hyaline cartilage.
(3) Each rib is a flat thin bone and all the ribs are connected dorsally to the thoracic vertebrae and ventrally to the sternum.
(4) There are seven pairs of vertebrosternal, three pairs of vertebrochondral and two pairs of vertebral ribs.
✅ (4) There are seven pairs of vertebrosternal, three pairs of vertebrochondral and two pairs of vertebral ribs.
32. Out of ‘X’ pairs of ribs in humans only ‘Y’ pairs are true ribs. Select the option that correctly represents values of X and Y and provides their explanation.
(1) X = 12, Y = 5 True ribs are attached dorsally to vertebral column and sternum on the two ends
(2) X = 24, Y = 2 The true ribs are dorsally attached to vertebral column but are free on ventral side
(3) X = 24, Y = 12 True ribs are dorsally attached to vertebral column but are free on ventral side
(4) X = 12, Y = 7 True ribs are attached dorsally to vertebral column and ventrally to the sternum (NEET 2017)
✅ (4) X = 12, Y = 7 True ribs are attached dorsally to vertebral column and ventrally to the sternum
33. The pivot joint between atlas and axis is a type of
(1) cartilaginous joint
(2) synovial joint
(3) saddle joint
(4) fibrous joint (NEET 2017)
✅ (2) synovial joint
Model Questions
34. Number of bones in Human Axial skeletal system is
(1) 206
(2) 80
(3) 126
(4) 29
✅ (2) 80
35. Which of the following cranial bones are paired?
(1) Frontal & temporal
(2) Parietal & temporal
(3) Sphenoid & ethmoid
(4) Occipital & sphenoid
✅ (2) Parietal & temporal
36. The vertebral formula of human is
(1) C₇T₁₂L₅S₍₄₎C₍₅₎
(2) C₇T₁₂L₅S₍₅₎C₍₄₎
(3) C₇T₁₂L₅ S₍₅₎C₍₅₎
(4) C₇T5L12S₍₅₎C₍₆₎
✅ (2) C₇T₁₂L₅S₍₅₎C₍₄₎
37. Which of the following form thoracic cage of man?
(1) Ribs, sternum & thoracic vertebrae
(2) Ribs & sternum
(3) Ribs & thoracic vertebrae
(4) Ribs, sternum & lumbar vertebrae
✅ (1) Ribs, sternum & thoracic vertebrae
38. Which of the following is known as ‘floating ribs’?
(1) 11ᵗʰ & 12ᵗʰ pairs
(2) 8ᵗʰ, 9ᵗʰ & 10ᵗʰ pairs
(3) 1ˢᵗ to 7ᵗʰ pairs
(4) 1ˢᵗ, 2ⁿᵈ & 3ʳᵈ pairs
✅ (1) 11ᵗʰ & 12ᵗʰ pairs
39. Match the following columns:
a b c d
(1) 2 4 1 3
(2) 3 4 2 1
(3) 4 3 1 2
(4) 2 1 4 3
✅ (4) 2 1 4 3
40. Appendicular skeleton comprises
(1) Sternum & ribs
(2) Cranial & facial bones
(3) Limbs & girdles
(4) Vertebral column
✅ (3) Limbs & girdles
41. Select the incorrectly matched pair.
(1) Collar bone - Clavicle
(2) Shoulder bone - Scapula
(3) Ankle bones - Tarsals
(4) Palm bones - Carpals
✅ (4) Palm bones - Carpals
42. Pelvic girdle consists
(1) Ischium & pubis
(2) Ileum & pubis
(3) Ilium & Ischium
(4) Both A & C
✅ (4) Both A & C
43. Phalangeal formula is
(1) 2,3,3,3,3
(2) 3,3,3,3,2
(3) 2,3,2,3,2
(4) 2,3,3,3,2
✅ (1) 2,3,3,3,3
44. Label P, Q, R, S and T in the following figure.
(1) P= Ulna, Q= Radius, R= Carpals, S= Metacarpals, T= Phalanges
(2) P= Radius, Q= Ulna, R= Carpals, S= Metacarpals, T= Phalanges
(3) P= Ulna, Q= Radius, R= Metacarpals, S= Carpals, T= Phalanges
(4) P= Radius, Q= Ulna, R= Carpals, S= Phalanges, T= Metacarpals
✅ (2) P= Radius, Q= Ulna, R= Carpals, S= Metacarpals, T= Phalanges
45. Glenoid cavity is found in
(1) Humerus
(2) Pectoral girdle
(3) Pelvic girdle
(4) Skull
✅ (2) Pectoral girdle
46. The joints between the two vertebrae are
(1) Gliding
(2) Fibrous
(3) Pivot
(4) Cartilaginous
✅ (4) Cartilaginous
47. Match the following:
a b c d
(1) 2 1 4 3
(2) 4 3 1 2
(3) 3 4 2 1
(4) 2 4 1 3
✅ (4) 2 4 1 3
48. Which of the following is imperfectly developed ball and socket joint?
(1) Gliding joint
(2) Pivot joint
(3) Saddle joint
(4) Hinge joint
✅ (3) Saddle joint
Topic 3: DISORDERS OF MUSCULAR & SKELETAL SYSTEMS
NEET: Previous Years Questions
49. Which of the following are Autoimmune disorders?
A. Myasthenia gravis
B. Rheumatoid arthritis
C. Gout
D. Muscular dystrophy
E. Systemic Lupus Erythematosus (SLE)
Choose the most appropriate answer from the options given below:
(1) A, B & D only
(2) A, B & E only
(3) B, C & E only
(4) C, D & E only (NEET 2024)
✅ (2) A, B & E only
50. Chronic autoimmune disorder affecting neuro-muscular junction leading to fatigue, weakening and paralysis of skeletal muscle is called as:
(1) Arthritis
(2) Muscular dystrophy
(3) Myasthenia gravis
(4) Gout (NEET 2021)
✅ (3) Myasthenia gravis
51. Which of the following muscular disorders is inherited? (NEET 2019)
(1) Tetany
(2) Muscular dystrophy
(3) Myasthenia gravis
(4) Botulism
✅ (2) Muscular dystrophy
52. Which of the following hormones can play a significant role in osteoporosis? (NEET 2018)
(1) Aldosterone and Prolactin
(2) Progesterone and Aldosterone
(3) Estrogen and Parathyroid hormones
(4) Parathyroid hormones and Prolactin
✅ (3) Estrogen and Parathyroid hormones
53. Osteoporosis, an age-related disease of skeletal system, may occur due to
(1) immune disorder affecting neuromuscular junction leading to fatigue
(2) high concentration of Ca++ and Na+
(3) decreased level of estrogen
(4) accumulation of uric acid leading to inflammation of joints. (NEET-II 2016)
✅ decreased level of estrogen
Model Questions
54. Which of the following statement is not concerned with Myasthenia gravis?
(1) It is an auto immune disorder.
(2) Rapid muscle spasm due to low Ca2+ in body fluid.
(3) It affects neuromuscular junction.
(4) It leads to fatigue, weakening and paralysis of skeletal muscles.
✅ (2) Rapid muscle spasm due to low Ca2+ in body fluid.
55. Progressive degeneration of skeletal muscles is called
(1) Muscular dystrophy
(2) Myasthenia gravis
(3) Myocardial infarction
(4) Osteoporosis
✅ (1) Muscular dystrophy
56. An age-related disorder characterized by decreased bone mass and increased chances of fractures is
(1) Gout
(2) Muscular dystrophy
(3) Osteoporosis
(4) Arthritis
✅ (3) Osteoporosis
57. Inflammation of joints due to accumulation of uric acid crystals is
(1) Arthritis
(2) Keratitis
(3) Tetany
(4) Gout
✅ (4) Gout